LL-37
C₂₀₅H₃₄₀N₆₀O₅₃
Human cathelicidin antimicrobial peptide studied for innate immunity and wound healing.
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LL-37 is the only human cathelicidin antimicrobial peptide, derived from the C-terminal domain of the 18 kDa hCAP18 protein. It exhibits broad-spectrum antimicrobial activity against bacteria, fungi, and viruses through membrane disruption. Beyond direct antimicrobial action, research has demonstrated immunomodulatory effects including chemotaxis, angiogenesis promotion, and wound healing enhancement. It is a critical compound in innate immunity research.
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