Neurological
PE-22-28
COA VERIFIED

PE-22-28

C₃₄H₅₃N₉Oβ‚ˆ

Neurological
HPLC PURITY98.5%

Spadin analog studied for TREK-1 channel modulation and antidepressant-like effects.

Molecular Weight
719.84 g/mol
Appearance
White lyophilized powder
Storage
Store at -20Β°C.

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Quantity

1
$34.99

PE-22-28 is a synthetic peptide analog derived from spadin, a natural inhibitor of the TREK-1 potassium channel. TREK-1 channels are involved in mood regulation, and their inhibition has been associated with antidepressant-like effects. Research has demonstrated rapid-onset mood-modulating activity in animal models, with PE-22-28 showing improved potency and stability compared to the parent spadin molecule.

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