PT-141 (Bremelanotide)
C₅₀H₆₈N₁₄O₁₀
Melanocortin receptor agonist studied for sexual function via central nervous system pathways.
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PT-141 (Bremelanotide) is a cyclic heptapeptide melanocortin receptor agonist, primarily targeting MC3R and MC4R. Unlike PDE5 inhibitors that act peripherally, PT-141 modulates sexual function through central nervous system pathways. Originally derived from the tanning peptide Melanotan II, research has focused on its effects on sexual desire and arousal through hypothalamic melanocortin signaling.
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