
ARA-290
Cβ βHββNββOββ
Erythropoietin-derived peptide studied for tissue protection without erythropoietic activity.
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ARA-290 is a synthetic 11-amino acid peptide derived from the erythropoietin (EPO) molecule. It selectively activates the innate repair receptor (IRR, a heterodimer of EPO-R and Ξ²cR) without stimulating erythropoiesis. Research has demonstrated anti-inflammatory, neuroprotective, and tissue-repair effects through IRR activation. Studies have explored applications in neuropathic pain, diabetic complications, and cardiac tissue protection.
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